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IMPACT2 Disease
The name of a disease policy model. For example, the current development is IMPACT2CHD. If we modify the DISEASE MODEL adding for example a state for STROKE, we can call this new “model”, IMPACT2CVD. In time, this nomenclature will highlight the generic nature of the modelling environment for non-communicable disease.
IMPACT2Disease
The MODEL DATASET for the left hand side module.
Incidence
An epidemiological term that describes the occurrence of a new event in the simulation. It is generally expressed as number of “new cases” /population at risk taking into account time. It can be expressed as a density (number of new cases/person-time) or in cumulative form (number of new cases/population in a given period of time).
It could be a tricky concept, since it is not always easy to define what a new case is. For the simulation, a practical definition of new case could be “the first visit to a given state”.
For example, a healthy individual that develops is or her first Acute myocardial infarction (AMI) is an “incident AMI”. If this patient form the AMI state enters the heart failure state for the first time, is considered an “incident heart failure patient”. However, a patient that re-enters the AMI state after an AMI, is not an incident AMI.
It also been used to define the event of an individual developing any of the CVD starting states coming from the left side.
Intervention
Drug, procedure or policy decision that might have an effect on incidence (left side) or hazards (right side)
INTERVENTION SET
A group of interventions that and user can decide to work with.
INTERVENTIONS EFFECTS
is a set of INTERVENTIONS that can modify a specific PROBABILITY DISTRIBUTION associated with an EDGE between two NODES. These are the COMBINED RELATIVE RISK REDUCTION of an INTERVENTION SET
Life expectancy
Life expectancy is a statistical measure of the average life span (average length of survival) of a specified population. It most often refers to the expected age to be reached before death for a given human population (by nation, by year of birth, or by other demographic variables).
It is usually calculated using a life table
Life table
A life table (also called a mortality table or actuarial table) is a table which shows, for a person at each age, what the probability is that they die before their next birthday. From this starting point, a number of statistics can be derived and thus also included in the table:
the probability of surviving any particular year of age remaining life expectancy for people at different ages the proportion of the original birth cohort still alive estimates of a cohort's longevity characteristics.

University of Liverpool

  • University of Manchester
  • National Institute of Health Research
  • Medical Research Council