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Acute Coronary Syndromes
Refer to a subset of CHD patients with acute myocardial infarction or unstable angina. The common factor is that these patients are usually hospitalized and are eligible for complex, in-hospital interventions.
Acute myocardial infarction
The sudden occlusion of one of the arteries feeding the heart muscle, leading ultimately to heart muscle loss and other complications. Usually treated in hospital with complex treatments. Most treatments are aimed to limit the amount of muscle loss, to decrease the immediate risk of death and to prevent recurrence of the myocardial infarction. High case fatality rate, and usually the timescale for the relevant outcomes are measured in days rather than months or year.
Adherence (proposed name for this functionality is UPTAKE)
This term refers to a key component of the right side. We modelled the effects of the interventions by a reduction in a relevant hazard using a relative risk reduction associated to an intervention. However, the effect of a drug only is possible if: the drug is prescribed, the drug is available, and the patient adheres to the treatment. Collectively, we refer to these conditional as “uptake” and we proposed to use this term to refer to this functionality, since adherence is only a component of the idea.
ASSIGN
A cardiovascular risk function, used to create a number of “incident” cases to be fed into the Disease module.

University of Liverpool

  • University of Manchester
  • National Institute of Health Research
  • Medical Research Council